{"product_id":"grk2-monoclonal-antibody-bt-mca3220","title":"GRK2 Monoclonal Antibody - BT-MCA3220","description":"\u003cp\u003eGRK2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3220-50, BT-MCA3220-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: GRK2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat, Monkey\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3F8\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: GRK2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human GRK2 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 80kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P25098\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: GRK2, BARK1, FLJ16718, BETA-ARK1, ADRBK1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 156\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238596075699,"sku":"BT-MCA3220-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238596108467,"sku":"BT-MCA3220-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ce564757-9fb2-498a-b160-027169018b09.png?v=1769382909","url":"https:\/\/afsbio.com\/products\/grk2-monoclonal-antibody-bt-mca3220","provider":"AFSBio Inc.","version":"1.0","type":"link"}