{"product_id":"grp3-polyclonal-antibody-bt-ap15793","title":"GRP3 Polyclonal Antibody - BT-AP15793","description":"\u003cp\u003eGRP3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15793-20, BT-AP15793-50, BT-AP15793-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP\/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RASGRP3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Ras guanyl-releasing protein 3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8IV61\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Ras guanyl-releasing protein 3;Calcium and DAG-regulated guanine nucleotide exchange factor III;Guanine nucleotide exchange factor for Rap1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 25780\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239159783603,"sku":"BT-AP15793-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239159816371,"sku":"BT-AP15793-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239159849139,"sku":"BT-AP15793-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f4b547a7-bd8e-40df-9108-0c8fa19f4934.png?v=1769389933","url":"https:\/\/afsbio.com\/products\/grp3-polyclonal-antibody-bt-ap15793","provider":"AFSBio Inc.","version":"1.0","type":"link"}