{"product_id":"grp78-bip-rabbit-pab-es8607","title":"GRP78 BiP rabbit pAb - ES8607","description":"\u003cp\u003eGRP78 BiP rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES8607-50, ES8607-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.[provided by RefSeq, Sep 2010],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: 78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca (2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000.IHC-p\/f:1:50-300. ELISA 1:10000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat; Fish\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide from human protein at AA range: 505-570\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 78kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 3309\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P11021\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Endoplasmic reticulum lumen. Melanosome. Cytoplasm. Cell surface. Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545). Localizes to the cell surface of epithelial cells in response to high levels of free iron (PubMed:20484814, PubMed:24355926, PubMed:27159390).\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202387861683,"sku":"ES8607-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202387894451,"sku":"ES8607-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_9b7fa7b8-dbfe-4b74-a80e-2b227d954016.png?v=1767128046","url":"https:\/\/afsbio.com\/products\/grp78-bip-rabbit-pab-es8607","provider":"AFSBio Inc.","version":"1.0","type":"link"}