{"product_id":"gsk3α-β-rabbit-pab-es2486","title":"GSK3α\/β rabbit pAb - ES2486","description":"\u003cp\u003eGSK3α\/β rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES2486-50, ES2486-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: glycogen synthase kinase 3 alpha (GSK3A) Homo sapiens This gene encodes a multifunctional Ser\/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: GSK3A; Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine\/threonine-protein kinase GSK3A; GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine\/threonine-protein kinase GSK3B\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat; Drosophila; Drosophila\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human GSK3 alpha\/beta. AA range:246-295\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 51, 46kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 2931\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P49840\/P49841\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: mitochondrion, cytosol, beta-catenin destruction complex, postsynapse,\u003c\/p\u003e \n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202079776947,"sku":"ES2486-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202079809715,"sku":"ES2486-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_213fba5f-7fd0-486f-a613-92fd65fd147c.png?v=1767121398","url":"https:\/\/afsbio.com\/products\/gsk3%ce%b1-%ce%b2-rabbit-pab-es2486","provider":"AFSBio Inc.","version":"1.0","type":"link"}