{"product_id":"gsk3β-phospho-ser9-rabbit-pab-es1420","title":"GSK3β (phospho Ser9) rabbit pAb - ES1420","description":"\u003cp\u003eGSK3β (phospho Ser9) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES1420-50, ES1420-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine\/threonine-protein kinase GSK3B\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized phospho-peptide around the phosphorylation site of human GSK3β (phospho Ser9)\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 47kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 2932\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P49841\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm. Nucleus. Cell membrane. The phosphorylated form shows localization to cytoplasm and cell membrane (PubMed:20937854). The MEMO1-RHOA-DIAPH1 signaling pathway controls localization of the phosphorylated form to the cell membrane (PubMed:20937854).\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202013028531,"sku":"ES1420-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202013061299,"sku":"ES1420-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_ade58ae2-4b9b-47db-b591-5a1433066d62.png?v=1767119931","url":"https:\/\/afsbio.com\/products\/gsk3%ce%b2-phospho-ser9-rabbit-pab-es1420","provider":"AFSBio Inc.","version":"1.0","type":"link"}