{"product_id":"gsk3-alpha-beta-monoclonal-antibody-mb10403","title":"GSK3 alpha\/beta Monoclonal Antibody-MB10403","description":"\u003cp\u003eGSK3 alpha\/beta Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB10403-50, MB10403-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P49840\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat,Hamster\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000\u003c\/p\u003e  \n\n\u003cp\u003eBackground: GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of GSK3 alpha + beta in Jurkat, rat Brain, C6, CHO-K1, HelaLysates using GSK3 alpha\/beta antibody.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 51 kDa; Observed MW: 51,47 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Serine\/threonine-protein kinase GSK3A\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: A synthetic peptide of human GSK3 alpha\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42935428743347,"sku":"MB10403-50","price":415.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42935428776115,"sku":"MB10403-100","price":640.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_755d3387-579a-4b89-afdd-ab3eeacc2fe1.jpg?v=1704370493","url":"https:\/\/afsbio.com\/products\/gsk3-alpha-beta-monoclonal-antibody-mb10403","provider":"AFSBio Inc.","version":"1.0","type":"link"}