{"product_id":"gsk3beta-polyclonal-antibody-bt-ap03849","title":"GSK3Beta Polyclonal Antibody - BT-AP03849","description":"\u003cp\u003eGSK3Beta Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03849-20, BT-AP03849-50, BT-AP03849-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The glycogen synthase kinase 3 beta encoded by GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for GSK3B.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: GSK3B\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: GSK3beta Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 46744\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P49841; Mouse: Q9WV60; Rat: P18266\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine\/threonine-protein kinase GSK3B\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 2932; Mouse: 56637; Rat: 84027\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240349819059,"sku":"BT-AP03849-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240349851827,"sku":"BT-AP03849-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240349884595,"sku":"BT-AP03849-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_bc27698b-227d-461f-ad25-461a1ec5e12d.png?v=1769407179","url":"https:\/\/afsbio.com\/products\/gsk3beta-polyclonal-antibody-bt-ap03849","provider":"AFSBio Inc.","version":"1.0","type":"link"}