{"product_id":"gsta2-polyclonal-antibody-bs70857","title":"GSTA2 Polyclonal Antibody-BS70857","description":"\u003cp\u003eGSTA2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS70857-50, BS70857-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P09210\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eGSTA2 Polyclonal Antibody-BS70857\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB 1:500 - 1:2000 \u003cbr\u003e\nIHC 1:50 - 1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: GSTA2 polyclonal antibody detects endogenous levels of GSTA2 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 26 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of extracts of various cells, using GSTA2 antibody., Immunohistochemistry of paraffin-embedded human prostate cancer using GSTA2 antibody at dilution of 1:100 (x40 lens) .\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: GST2; GTA2; GTH2; GSTA2-2;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Recombinant protein of human GSTA2.\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42962810634419,"sku":"BS70857-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42962810667187,"sku":"BS70857-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_51d79072-f7cc-46b0-aecd-191565ba9ef4.jpg?v=1705319069","url":"https:\/\/afsbio.com\/products\/gsta2-polyclonal-antibody-bs70857","provider":"AFSBio Inc.","version":"1.0","type":"link"}