{"product_id":"gstm1-polyclonal-antibody-bs77289","title":"GSTM1 Polyclonal Antibody-BS77289","description":"GSTM1 Polyclonal Antibody\n\nSizes: 50µl, 100µl\n\nCatalogue Numbers:  BS77289-50, BS77289-100\n\nProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\n\nSwiss-Prot: P09488\n\nHost: Rabbit\n\nReactivity: Human, Mouse, Rat\n\nApplications: WB, IF\/ICC\n\nAll Applications: WB,1:500 - 1:2000   |   IF\/ICC,1:50 - 1:100\n\nBackground: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]\n\nPurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\n\nStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\n\nSpecificity: Unmodification \n\nExtra Notes: Western blot analysis of extracts of various cell lines, using at 1:1000 dilution.\nSecondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.\nLysates\/proteins: 25ug per lane.\nBlocking buffer: 3% nonfat dry milk in TBST.\nDetection: ECL Basic Kit.\nExposure time: 180s.\n\nNote: For research use only, not for use in diagnostic procedure.\n\nBioworld Molecular Weight: 28KDa\n\nAlternative Name: GST1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4; GTM1; H-B; MU; MU-1; GSTM1\n\nImmunogen: Recombinant fusion protein of human GSTM1(NP_666533.1).\n\nConjugate: Unconjugated\n\nModification: Unmodified ","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42924615270579,"sku":"BS77289-50","price":334.88,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42924615303347,"sku":"BS77289-100","price":576.38,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_cdf220a3-53dd-4430-a1b1-aa46c19e7416.jpg?v=1703937011","url":"https:\/\/afsbio.com\/products\/gstm1-polyclonal-antibody-bs77289","provider":"AFSBio Inc.","version":"1.0","type":"link"}