{"product_id":"gstp1-monoclonal-antibody-bt-mca4480","title":"GSTP1 Monoclonal Antibody - BT-MCA4480","description":"\u003cp\u003eGSTP1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4480-50, BT-MCA4480-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: GSTP1 (glutathione-S-transferase, pi 1), also called GST3\/DFN7, is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (\u0026gt;90%) of prostate carcinomas and is associated with transcriptional down-regulation.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular, Neuroscience, Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: GSTP1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3F2C2\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: GSTP1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human GSTP1 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 23kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P09211\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PI, DFN7, GST3, FAEES3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 2950\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238648930483,"sku":"BT-MCA4480-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238648963251,"sku":"BT-MCA4480-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_83557ce2-54de-4fc5-a6da-a70a3d094551.png?v=1769383400","url":"https:\/\/afsbio.com\/products\/gstp1-monoclonal-antibody-bt-mca4480","provider":"AFSBio Inc.","version":"1.0","type":"link"}