{"product_id":"gtf3a-polyclonal-antibody-e-ab-19973","title":"GTF3A Polyclonal Antibody - E-AB-19973","description":"\u003cp\u003eGTF3A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-19973-60, E-AB-19973-120, E-AB-19973-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: GTF3A\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: AP 2; AP2; Factor A; General transcription factor 3A; General transcription factor IIIA; GTF 3A; GTF3A; TF3A; TFIIIA; Transcription factor 3A; Transcription factor IIIA\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q92664\u003c\/p\u003e\n\n\u003cp\u003eBackground: The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.68 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human GTF3A\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 42 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43143937425587,"sku":"E-AB-19973-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43143937458355,"sku":"E-AB-19973-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43143937491123,"sku":"E-AB-19973-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_aa74f95c-8409-4933-ba95-61f216dbed04.png?v=1710243986","url":"https:\/\/afsbio.com\/products\/gtf3a-polyclonal-antibody-e-ab-19973","provider":"AFSBio Inc.","version":"1.0","type":"link"}