{"product_id":"hace1-polyclonal-antibody-bt-ap09806","title":"HACE1 Polyclonal Antibody - BT-AP09806","description":"\u003cp\u003eHACE1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09806-20, BT-AP09806-50, BT-AP09806-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilmandapos;s tumor.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Cell biology; Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HACE1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: E3 ubiquitin-protein ligase HACE1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8IYU2; Mouse: Q3U0D9; Rat: D3ZBM7\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: E3 ubiquitin-protein ligase HACE1;EC 6.3.2.-;HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 57531\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239162077363,"sku":"BT-AP09806-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239162110131,"sku":"BT-AP09806-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239162142899,"sku":"BT-AP09806-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_6f92f027-76ab-4e0b-b12d-cc741914dc05.png?v=1769389966","url":"https:\/\/afsbio.com\/products\/hace1-polyclonal-antibody-bt-ap09806","provider":"AFSBio Inc.","version":"1.0","type":"link"}