HAMA Blocking Reagent (10 mg)

HAMA Blocking Reagent (10 mg)

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$320.58
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The presence in human serum of Human Anti-Mouse antibodies (HAMA) is a major concern in immunoassays. Indeed, HAMA are often associated with inaccurate results and false positives because they can bind to both capture and detection antibodies and can generate non-specific immunoassay signals. The provided HAMA Blocking Reagent specifically binds to HAMA, minimizing their interference and significantly reducing the number of false positives. Simply spike our HAMA Blocking Reagent into your immunoassay reagent(s) to 5-50 ug/mL (optimum concentration is assay dependent).

 

Product Data Sheet Download PDF
MSDS Download PDF
Catalog # A2010010
Size 10 mg
Other Names Heterophilic Immunoglobulin Blocking Reagent
Concentration 2 mg/mL
Purity Affinity purified
Storage 2-8°C (short term). -20°C (long term). Avoid repeated freeze-thaw.
Supplied as Liquid solution
Buffer PBS 1x
Keywords HAMA

References

  1. Reinsberg J. (1996). Different efficacy of various blocking reagents to eliminate interferences by human antimouse antibodies with a two-site immunoassay. Clin Biochem. 1996 Apr;29(2):145-8.
  2. Bolstad N, Warren DJ, Nustad K. Heterophilic antibody interference in immunometric assays. Best Pract Res Clin Endocrinol Metab. 2013 Oct;27(5):647-61.
  3. Lippi G, Aloe R, Meschi T, Borghi L, Cervellin G. Interference from heterophilic antibodies in troponin testing. Case report and systematic review of the literature. Clin Chim Acta. 2013 Nov 15;426:79-84.