{"product_id":"hamartin-rabbit-monoclonal-antibody-bs41107","title":"Hamartin Rabbit Monoclonal Antibody - BS41107","description":"\u003cp\u003eHamartin Rabbit Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS41107-50, BS41107-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimμlated phosphorylation of S6K1 and EIF4EBP1 by negatively regμlating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubμle-mediated protein transport, but this seems to be due to unregμlated mTOR signaling.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC\/IF, FC\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Hamartin, kiaa0243, LAM, TSC, Tsc1, Tuberous sclerosis 1,\u003c\/p\u003e \n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human Hamartin\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1000~1:5000 IHC 1:50~1:200 ICC\/IF 1:50~1:200 FC 1:200\u003c\/p\u003e\n\n\u003cp\u003ePurification: Affinity-chromatography\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Hamartin Antibody detects endogenous levels of total Hamartin\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 150kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: Q92574\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45937022795955,"sku":"BS41107-50","price":289.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45937022828723,"sku":"BS41107-100","price":492.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image.jpg?v=1788296056","url":"https:\/\/afsbio.com\/products\/hamartin-rabbit-monoclonal-antibody-bs41107","provider":"AFSBio Inc.","version":"1.0","type":"link"}