{"product_id":"hap1-polyclonal-antibody-bs74040","title":"HAP1 Polyclonal Antibody-BS74040","description":"\u003cp\u003eHAP1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100µl, 1ml\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS74040-100, BS74040-1ml\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P54257\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: HAP1 polyclonal antibody detects endogenous levels of HAP1 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 76 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of HAP1 polyclonal antibody at 1:1000 dilution.\u003cbr\u003e\nLysates\/proteins: 25ug per lane.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: HAP1; HAP2; HIP5; HLP; hHLP1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human HAP1.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"100µl","offer_id":43044025991347,"sku":"BS74040-100","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"1ml","offer_id":43044026024115,"sku":"BS74040-1ml","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_dd240db0-0ffa-4e67-afb2-d2d5a5e70d97.jpg?v=1707738628","url":"https:\/\/afsbio.com\/products\/hap1-polyclonal-antibody-bs74040","provider":"AFSBio Inc.","version":"1.0","type":"link"}