{"product_id":"haptoglobin-polyclonal-antibody-bt-ap09816","title":"Haptoglobin Polyclonal Antibody - BT-AP09816","description":"\u003cp\u003eHaptoglobin Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09816-20, BT-AP09816-50, BT-AP09816-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and\/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohnandapos;s disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinsonandapos;s disease, and a reduced incidence of Plasmodium falciparum malaria. The protein encoded also exhibits antimicrobial activity against bacteria. A similar duplicated gene is located nex\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular; Cell biology; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HP\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Haptoglobin\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P00738; Mouse: Q61646\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Haptoglobin;Zonulin [Cleaved into: Haptoglobin alpha chain; Haptoglobin beta chain]; Haptoglobin; Zonulin; Haptoglobin alpha chain; Haptoglobin beta chain;\u003c\/p\u003e \n\n\u003cp\u003eGeneID: Human: 3240; Mouse: 15439\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239162634419,"sku":"BT-AP09816-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239162667187,"sku":"BT-AP09816-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239162699955,"sku":"BT-AP09816-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e1822075-a155-484e-802f-fbdeb33d10d9.png?v=1769389971","url":"https:\/\/afsbio.com\/products\/haptoglobin-polyclonal-antibody-bt-ap09816","provider":"AFSBio Inc.","version":"1.0","type":"link"}