{"product_id":"hax1-polyclonal-antibody-e-ab-61005","title":"HAX1 Polyclonal Antibody - E-AB-61005","description":"\u003cp\u003eHAX1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-61005-60, E-AB-61005-120, E-AB-61005-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: HAX1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: HAX1; HCLSBP1; HS1BP1; SCN3\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Cell Biology,Epigenetics and Nuclear Signaling,Metabolism\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: O00165\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human HAX1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IF 1:10-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 14kDa\/21kDa\/26kDa\/28kDa\/31kDa\/32kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 36kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146135797939,"sku":"E-AB-61005-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146135830707,"sku":"E-AB-61005-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146135863475,"sku":"E-AB-61005-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_3c406609-675d-4bc0-8805-241649b4af09.png?v=1710291121","url":"https:\/\/afsbio.com\/products\/hax1-polyclonal-antibody-e-ab-61005","provider":"AFSBio Inc.","version":"1.0","type":"link"}