{"product_id":"hbg1-polyclonal-antibody-e-ab-91025","title":"HBG1 Polyclonal Antibody - E-AB-91025","description":"\u003cp\u003eHBG1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-91025-60, E-AB-91025-120, E-AB-91025-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: HBG1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: HBG1; HBG-T2; HBGA; HBGR; HSGGL1; PRO2979\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P69891\u003c\/p\u003e\n\n\u003cp\u003eBackground: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human HBG1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 16kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 12KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146583179443,"sku":"E-AB-91025-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146583212211,"sku":"E-AB-91025-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146583244979,"sku":"E-AB-91025-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_9c2d5dcd-1929-4cb8-b80b-90cc7503f3de.png?v=1710297888","url":"https:\/\/afsbio.com\/products\/hbg1-polyclonal-antibody-e-ab-91025","provider":"AFSBio Inc.","version":"1.0","type":"link"}