{"product_id":"hbp1-rabbit-pab-es2495","title":"HBP1 rabbit pAb - ES2495","description":"\u003cp\u003eHBP1 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES2495-50, ES2495-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4., similarity:Contains 1 AXH domain., similarity:Contains 1 HMG box DNA-binding domain., subunit:Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: HBP1; HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat; Monkey\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human HBP1. AA range:431-480\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 57kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 26959\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: O60381\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202080334003,"sku":"ES2495-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202080366771,"sku":"ES2495-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_faac07f1-d976-4e95-92f7-5784bc760ad6.png?v=1767121412","url":"https:\/\/afsbio.com\/products\/hbp1-rabbit-pab-es2495","provider":"AFSBio Inc.","version":"1.0","type":"link"}