{"product_id":"hbs1l-polyclonal-antibody-e-ab-90044","title":"HBS1L Polyclonal Antibody - E-AB-90044","description":"\u003cp\u003eHBS1L Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-90044-60, E-AB-90044-120, E-AB-90044-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: HBS1L\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: HBS1L; EF-1a; ERFS; HBS1; HSPC276; eRF3c\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9Y450\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia\/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human HBS1L\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:1000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 70kDa\/75kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 75kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43148698452147,"sku":"E-AB-90044-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43148698484915,"sku":"E-AB-90044-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43148698517683,"sku":"E-AB-90044-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_421614e1-4dc4-46f6-b17d-61410e6c3ef8.png?v=1710328293","url":"https:\/\/afsbio.com\/products\/hbs1l-polyclonal-antibody-e-ab-90044","provider":"AFSBio Inc.","version":"1.0","type":"link"}