{"product_id":"hcn4-polyclonal-antibody-bt-ap09844","title":"HCN4 Polyclonal Antibody - BT-AP09844","description":"\u003cp\u003eHCN4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09844-20, BT-AP09844-50, BT-AP09844-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cardiovascular; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HCN4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Potassium\/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9Y3Q4; Mouse: O70507; Rat: Q9JKA7\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Potassium\/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 10021\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239164403891,"sku":"BT-AP09844-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239164436659,"sku":"BT-AP09844-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239164469427,"sku":"BT-AP09844-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_08cbbaef-7913-4733-b608-f02ecb139f3f.png?v=1769390000","url":"https:\/\/afsbio.com\/products\/hcn4-polyclonal-antibody-bt-ap09844","provider":"AFSBio Inc.","version":"1.0","type":"link"}