{"product_id":"hdac1-monoclonal-antibody-bt-mca2452","title":"HDAC1 Monoclonal Antibody - BT-MCA2452","description":"\u003cp\u003eHDAC1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2452-50, BT-MCA2452-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase\/acuc\/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HDAC1\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 1B6A7\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: HDAC1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human HDAC1 (AA: 321-482) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 55.1kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q13547\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HD1, RPD3, KDAC1, GON-10, RPD3L1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3065\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238388916403,"sku":"BT-MCA2452-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238388949171,"sku":"BT-MCA2452-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_fc83248d-32cf-4bd7-b119-b94739c45ba3.png?v=1769379761","url":"https:\/\/afsbio.com\/products\/hdac1-monoclonal-antibody-bt-mca2452","provider":"AFSBio Inc.","version":"1.0","type":"link"}