{"product_id":"hdac1-phospho-ser421-polyclonal-antibody-ra25652","title":"HDAC1 (phospho Ser421) Polyclonal Antibody - RA25652","description":"\u003cp\u003eHDAC1 (phospho Ser421) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA25652-50, RA25652-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: histone deacetylase 1 (HDAC1) Homo sapiens Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase\/acuc\/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: HDAC1; RPD3L1; Histone deacetylase 1; HD1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF (paraffin section) ; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 3065\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 62\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q13547\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121311735987,"sku":"RA25652-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121311768755,"sku":"RA25652-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_66835db1-6be3-45d6-9f19-e726e38c23c2.png?v=1773346308","url":"https:\/\/afsbio.com\/products\/hdac1-phospho-ser421-polyclonal-antibody-ra25652","provider":"AFSBio Inc.","version":"1.0","type":"link"}