{"product_id":"hdac1-polyclonal-antibody-e-ab-15711","title":"HDAC1 Polyclonal Antibody - E-AB-15711","description":"\u003cp\u003eHDAC1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-15711-60, E-AB-15711-120, E-AB-15711-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: HDAC1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: DKFZp686H12203; GON 10; HD1; HDAC 1; HDAC1; HDAC1; Histone deacetylase 1; Reduced potassium dependency yeast homolog like 1; RPD3; RPD3L1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q13547\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase\/acuc\/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.3 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human HDAC1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:200-1:1000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 55kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43143815561395,"sku":"E-AB-15711-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43143815594163,"sku":"E-AB-15711-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43143815626931,"sku":"E-AB-15711-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_999545c2-8c86-47c8-a3c1-d7fdc927f399.png?v=1710241937","url":"https:\/\/afsbio.com\/products\/hdac1-polyclonal-antibody-e-ab-15711","provider":"AFSBio Inc.","version":"1.0","type":"link"}