{"product_id":"hdac2-2d9-monoclonal-antibody-mb3020","title":"HDAC2 (2D9) Monoclonal Antibody-MB3020","description":"\u003cp\u003eHDAC2 (2D9) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB3020-50, MB3020-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q92769\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat,Monkey\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB,ICC\/IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IF: 1\/50-1\/200\u003c\/p\u003e  \n\n\u003cp\u003eBackground: In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of HDAC2 in THP-1, SH-SY5Y, K562, COS7, C6, 3T3 and HelaLysates using HDAC2 antibody.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 55 kDa; Observed MW: 60 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG2b\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: HDAC2; Histone deacetylase 2; HD2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant human HDAC2 protein fragments expressed in E.coli.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42932522385587,"sku":"MB3020-50","price":415.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42932522418355,"sku":"MB3020-100","price":640.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_b1cbbc1a-02f2-4fa9-85cf-5769c5d692a9.jpg?v=1704284446","url":"https:\/\/afsbio.com\/products\/hdac2-2d9-monoclonal-antibody-mb3020","provider":"AFSBio Inc.","version":"1.0","type":"link"}