{"product_id":"hdac3-monoclonal-antibody-bt-mca3164","title":"HDAC3 Monoclonal Antibody - BT-MCA3164","description":"\u003cp\u003eHDAC3 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3164-50, BT-MCA3164-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: HDAC3: histone deacetylase 3, also known as HD3, RPD3, RPD3-2. Entrez Protein NC_000005. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation\/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase\/acuc\/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HDAC3\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3A7B5\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: HDAC3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of HDAC3 (aa224-428) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 48.8kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: O15379\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HD3, RPD3, RPD3-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 8841\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238646702259,"sku":"BT-MCA3164-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238646735027,"sku":"BT-MCA3164-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_cabe0eb2-d5ec-4da1-ba9d-59d2447322f9.png?v=1769383381","url":"https:\/\/afsbio.com\/products\/hdac3-monoclonal-antibody-bt-mca3164","provider":"AFSBio Inc.","version":"1.0","type":"link"}