{"product_id":"hdac3-monoclonal-antibody-ra11351","title":"HDAC3 Monoclonal Antibody - RA11351","description":"\u003cp\u003eHDAC3 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA11351-50, RA11351-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: histone deacetylase 3 (HDAC3) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation\/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase\/acuc\/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat; Dog; Pig; Rabbit\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 8841\u003c\/p\u003e\n\n\u003cp\u003eSWISS: O15379\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45118974001331,"sku":"RA11351-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45118974034099,"sku":"RA11351-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b5b76ee5-f7e2-4d9c-8ae9-49d8b44fe0bf.png?v=1773343803","url":"https:\/\/afsbio.com\/products\/hdac3-monoclonal-antibody-ra11351","provider":"AFSBio Inc.","version":"1.0","type":"link"}