{"product_id":"hdac4-monoclonal-antibody-bt-mca2920","title":"HDAC4 Monoclonal Antibody - BT-MCA2920","description":"\u003cp\u003eHDAC4 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2920-50, BT-MCA2920-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation\/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase\/acuc\/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HDAC4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 7B2\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: HDAC4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human HDAC4 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS containing 0.05% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 119kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P56524\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HD4, HDACA, HA6116, HDAC-A, KIAA0288, HDAC4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 9759\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238633005235,"sku":"BT-MCA2920-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238633038003,"sku":"BT-MCA2920-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5c6623c7-3568-45d7-8d81-6e477fe591bd.png?v=1769383262","url":"https:\/\/afsbio.com\/products\/hdac4-monoclonal-antibody-bt-mca2920","provider":"AFSBio Inc.","version":"1.0","type":"link"}