{"product_id":"hdac4-n-term-mouse-monoclonal-antibody-ra11357","title":"HDAC4 (N-term) Mouse Monoclonal Antibody - RA11357","description":"\u003cp\u003eHDAC4 (N-term) Mouse Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA11357-50, RA11357-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: histone deacetylase 4 (HDAC4) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation\/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase\/acuc\/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IP\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 9759\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 140\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P56524\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45119035211955,"sku":"RA11357-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45119035244723,"sku":"RA11357-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_14fe37a7-787e-417c-aa67-e813ba3d459e.png?v=1773344466","url":"https:\/\/afsbio.com\/products\/hdac4-n-term-mouse-monoclonal-antibody-ra11357","provider":"AFSBio Inc.","version":"1.0","type":"link"}