{"product_id":"hdac6-3b2-monoclonal-antibody-mb3031","title":"HDAC6 (3B2) Monoclonal Antibody-MB3031","description":"\u003cp\u003eHDAC6 (3B2) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB3031-50, MB3031-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9UBN7\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Involved in the regulation of many cellular processes, including cell migration, immune synapse formation, viral infection, and degradation of misfolded proteins. HDAC6 binds to both poly-ubiquitinated misfolded proteins and dynein motors, facilitating the transport of misfolded proteins to the aggresome. Required for subsequent recruitment of the autophagic machinery and clearance of aggresomes from the cell. Plays a key role in the protection against the deleterious effects of pathological protein aggregation that occurs in various diseases.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of HDAC6 in T47D, Jurkat CHO-K1 and CHO-K1 transfected by HDAC6fragment EGFP fusion proteinLysates using HDAC6 antibody.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 131 kDa; Observed MW: 160 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG2a\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant human HDAC6 protein expressed in E.coli.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42932523368627,"sku":"MB3031-50","price":415.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42932523401395,"sku":"MB3031-100","price":640.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_f8209035-e8ca-40e9-92a4-da23084e820d.jpg?v=1704284463","url":"https:\/\/afsbio.com\/products\/hdac6-3b2-monoclonal-antibody-mb3031","provider":"AFSBio Inc.","version":"1.0","type":"link"}