{"product_id":"hdac6-phospho-ser22-polyclonal-antibody-ra25663","title":"HDAC6 (phospho Ser22) Polyclonal Antibody - RA25663","description":"\u003cp\u003eHDAC6 (phospho Ser22) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA25663-50, RA25663-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: histone deacetylase 6 (HDAC6) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation\/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase\/acuc\/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF\/ICC; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 10013\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 131\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9UBN7\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121312522419,"sku":"RA25663-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121312555187,"sku":"RA25663-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e6cda5c3-a040-4392-b253-856e8019e0dc.png?v=1773346314","url":"https:\/\/afsbio.com\/products\/hdac6-phospho-ser22-polyclonal-antibody-ra25663","provider":"AFSBio Inc.","version":"1.0","type":"link"}