{"product_id":"hdac6-rabbit-monoclonal-antibody-bs40312","title":"HDAC6 Rabbit Monoclonal Antibody - BS40312","description":"\u003cp\u003eHDAC6 Rabbit Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS40312-50, BS40312-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Involved in the regμlation of many cellμlar processes, including cell migration, immune synapse formation, viral infection, and degradation of misfolded proteins. HDAC6 binds to both poly-ubiquitinated misfolded proteins and dynein motors, facilitating the transport of misfolded proteins to the aggresome. Required for subsequent recruitment of the autophagic machinery and clearance of aggresomes from the cell. Plays a key role in the protection against the deleterious effects of pathological protein aggregation that occurs in various diseases.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC\/IF, IP\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: HD 6, HDAC 6, Histone deacetylase 6 (HD6), JM 21,\u003c\/p\u003e \n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human HDAC6\u003c\/p\u003e \n\n\u003cp\u003eDilution: WB 1:5000~1:20000 IHC 1:50~1:200 ICC\/IF 1:100~1:500 IP 1:50\u003c\/p\u003e\n\n\u003cp\u003ePurification: Affinity-chromatography\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: HDAC6 Antibody detects endogenous levels of HDAC6\u003c\/p\u003e \n\n\u003cp\u003eMolecular Weight: 160kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: Q9UBN7\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45936892215475,"sku":"BS40312-50","price":289.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45936892248243,"sku":"BS40312-100","price":492.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image.jpg?v=1788296056","url":"https:\/\/afsbio.com\/products\/hdac6-rabbit-monoclonal-antibody-bs40312","provider":"AFSBio Inc.","version":"1.0","type":"link"}