{"product_id":"hdac6-rabbit-pab-a1732","title":"HDAC6 Rabbit pAb - A1732","description":"\u003cp\u003eHDAC6 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A1732-20, A1732-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation\/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase\/acuc\/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 131kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 160kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment)\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 10013\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9UBN7\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: HD6; JM21; CPBHM; PPP1R90; HDAC6\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, Signal Transduction, Cell Biology Developmental Biology, Autophagy, Cell Cycle, Cell Cycle Control-G1 S Checkpoint, Wnt -Catenin Signaling Pathway, Immunology Inflammation, NF-kB Signaling Pathway, Stem Cells.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: HDAC6\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189708251315,"sku":"A1732-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189708284083,"sku":"A1732-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_72c3acb7-526c-4086-8ebc-ef0961f7b9f1.png?v=1766433174","url":"https:\/\/afsbio.com\/products\/hdac6-rabbit-pab-a1732","provider":"AFSBio Inc.","version":"1.0","type":"link"}