{"product_id":"hdac6-rabbit-pab-a27908","title":"HDAC6 Rabbit pAb - A27908","description":"\u003cp\u003eHDAC6 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A27908-20, A27908-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Enables several functions, including cytoskeletal protein binding activity; protein lysine deacetylase activity; and ubiquitin binding activity. Involved in several processes, including positive regulation of type 2 mitophagy; protein destabilization; and tubulin deacetylation. Acts upstream of or within several processes, including aggresome assembly; neuron projection morphogenesis; and protein modification process. Located in several cellular components, including dendrite; microtubule cytoskeleton; and perikaryon. Part of cytoplasmic ubiquitin ligase complex. Is expressed in several structures, including central nervous system; early embryo; gut gland; lung; and metanephros. Human ortholog (s) of this gene implicated in chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia and polycystic liver disease 1. Orthologous to human HDAC6 (histone deacetylase 6) .\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\/ICC, IHC-P, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 126kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 140kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment) .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 15185\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9Z2V5\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Hd6; Sfc6; Hdac5; mHDA2\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:3000 - 1:18000 IF\/ICC, 1:100 - 1:200 IHC-P, 1:200 - 1:800 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling Chromatin Modifying Enzymes AcetylationStem Cells Signaling Pathways Wnt HDACsEpigenetics and Nuclear Signaling Chromatin Modifying Enzymes Acetylation HDACs Class II \/ Hda1 Class\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: HDAC6\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189889196211,"sku":"A27908-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189889228979,"sku":"A27908-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_946e8cff-0ef2-4414-a432-16cc4092a584.png?v=1766437527","url":"https:\/\/afsbio.com\/products\/hdac6-rabbit-pab-a27908","provider":"AFSBio Inc.","version":"1.0","type":"link"}