{"product_id":"hes3-rabbit-polyclonal-antibody-es10582","title":"HES3 Rabbit Polyclonal Antibody - ES10582","description":"\u003cp\u003eHES3 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES10582-50, ES10582-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human protein. at AA range: 20-100\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: HES3\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: HES3 Polyclonal Antibody detects endogenous levels of protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 20kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Human papillomavirus infection\u003c\/p\u003e\n\n\u003cp\u003eFunction: Domain: Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG)\u003cbr\u003e\nDomain: The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho\/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins\u003cbr\u003e\nFunction: Transcriptional repressor of genes that require a bHLH protein for their transcription\u003cbr\u003e\nSimilarity: Contains 1 basic helix-loop-helix (bHLH) domain\u003cbr\u003e\nSimilarity: Contains 1 Orange domain\u003cbr\u003e\nSubunit: Transcription repression requires formation of a complex with a corepressor protein of the Groucho\/TLE family\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Nucleus\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: HES3 BHLHB43\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Transcription factor HES-3 (Class B basic helix-loop-helix protein 43) (bHLHb43) (Hairy and enhancer of split 3)\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q61657\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: Q04667\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46314300080307,"sku":"ES10582-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46314300113075,"sku":"ES10582-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/hes3-rabbit-polyclonal-antibody-es10582","provider":"AFSBio Inc.","version":"1.0","type":"link"}