{"product_id":"hes4-polyclonal-antibody-bt-ap09872","title":"HES4 Polyclonal Antibody - BT-AP09872","description":"\u003cp\u003eHES4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09872-20, BT-AP09872-50, BT-AP09872-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG).,The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho\/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins.,Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'.,Contains 1 basic helix-loop-helix (bHLH) domain.,Contains 1 Orange domain.,subunit:Transcription repression requires formation of a complex with a corepressor protein of the Groucho\/TLE family.,\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Neuroscience\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: HES4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Transcription factor HES-4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9HCC6\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Transcription factor HES-4;hHES4;Class B basic helix-loop-helix protein 42;bHLHb42;Hairy and enhancer of split 4;bHLH factor Hes4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 57801\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239165518003,"sku":"BT-AP09872-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239165550771,"sku":"BT-AP09872-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239165583539,"sku":"BT-AP09872-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_af148ca8-3b0b-4756-825b-c5988ea89364.png?v=1769390018","url":"https:\/\/afsbio.com\/products\/hes4-polyclonal-antibody-bt-ap09872","provider":"AFSBio Inc.","version":"1.0","type":"link"}