{"product_id":"hexa-monoclonal-antibody-bt-mca3891","title":"HEXA Monoclonal Antibody - BT-MCA3891","description":"\u003cp\u003eHEXA Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3891-50, BT-MCA3891-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Tags and Cell Markers\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HEXA\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3F10\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: HEXA\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human HEXA expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 60.7kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P06865\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TSD\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3073\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238587719859,"sku":"BT-MCA3891-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238587752627,"sku":"BT-MCA3891-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2646a631-1bdb-47c2-a3eb-b7809a9af061.png?v=1769382842","url":"https:\/\/afsbio.com\/products\/hexa-monoclonal-antibody-bt-mca3891","provider":"AFSBio Inc.","version":"1.0","type":"link"}