{"product_id":"hfe-monoclonal-antibody-bt-mca3185","title":"HFE Monoclonal Antibody - BT-MCA3185","description":"\u003cp\u003eHFE Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3185-50, BT-MCA3185-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction, Stem cells, Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HFE\u003c\/p\u003e\n\n\u003cp\u003eApplications: ICC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3F1\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: HFE\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human HFE expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 40kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q30201\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HH, HFE1, HLA-H, MVCD7, TFQTL2, MGC103790, dJ221C16.10.1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3077\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238591750323,"sku":"BT-MCA3185-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238591783091,"sku":"BT-MCA3185-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_dae5da54-8152-4338-9635-39d99be68edc.png?v=1769382871","url":"https:\/\/afsbio.com\/products\/hfe-monoclonal-antibody-bt-mca3185","provider":"AFSBio Inc.","version":"1.0","type":"link"}