{"product_id":"hif-3alpha-polyclonal-antibody-bt-ap03970","title":"HIF-3Alpha Polyclonal Antibody - BT-AP03970","description":"\u003cp\u003eHIF-3Alpha Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03970-20, BT-AP03970-50, BT-AP03970-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by HIF3A (hypoxia inducible factor 3 alpha subunit) is the alpha-3 subunit of one of several alpha\/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for HIF3A.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HIF1A\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: HIF-3alpha Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 72433\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q66K72\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Hypoxia-inducible factor 3-alpha; HIF-3-alpha; HIF3-alpha; Basic-helix-loop-helix-PAS protein MOP7; Class E basic helix-loop-helix protein 17; bHLHe17; HIF3-alpha-1; Inhibitory PAS domain protein; IPA\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 64344\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240356896947,"sku":"BT-AP03970-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240356929715,"sku":"BT-AP03970-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240356962483,"sku":"BT-AP03970-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c3f2d3f5-0d0a-4a08-9d63-d2c63f3743c9.png?v=1769407305","url":"https:\/\/afsbio.com\/products\/hif-3alpha-polyclonal-antibody-bt-ap03970","provider":"AFSBio Inc.","version":"1.0","type":"link"}