{"product_id":"hif1β-arnt-rabbit-pab-a0972","title":"HIF1β\/ARNT Rabbit pAb - A0972","description":"\u003cp\u003eHIF1β\/ARNT Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A0972-20, A0972-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 87kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 87kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 405\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P27540\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: HIF1B; TANGO; bHLHe2; HIF1BETA; HIF-1beta; HIF1-beta; HIF-1-beta; HIF1β\/ARNT\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, Transcription Factors, Nuclear Receptor Signaling, Cancer, Invasion and Metastasis, Signal Transduction, mTOR Signaling Pathway, Endocrine Metabolism, Nucleotide metabolism, Cardiovascular, Angiogenesis, Hypoxia.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: ARNT\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189450498227,"sku":"A0972-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189450530995,"sku":"A0972-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_0794504c-5751-47fb-ae27-1a6baf5b74a2.png?v=1766427547","url":"https:\/\/afsbio.com\/products\/hif1%ce%b2-arnt-rabbit-pab-a0972","provider":"AFSBio Inc.","version":"1.0","type":"link"}