{"product_id":"hint1-n99-polyclonal-antibody-bs3011","title":"HINT1 (N99) Polyclonal Antibody-BS3011","description":"\u003cp\u003eHINT1 (N99) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS3011-50, BS3011-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P49773\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: IHC:1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Hint1, or histidine triad nucleotide-binding protein 1, belongs to the first branch of the HIT superfamily. It hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2. Hint1 also inhibits the activity of the transcription factors AP1, MITF and USF2, as well as influences the transcription process of the Wnt\/beta-catenin pathway. In addition, mammalian Hint1 has been suggested to have some tumor suppressor activity.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunohistochemistry (IHC) analyzes of Hint1 (N99) pAb in paraffin-embedded human prostate cancer tissue.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 14 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Hint1 (N99) polyclonal antibody detects endogenous levels of Hint1 protein.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Histidine triad nucleotide-binding protein 1; Adenosine 5'-monophosphoramidase; Protein kinase C inhibitor 1; Protein kinase C-interacting protein 1; PKCI-1; HINT1; HINT; PKCI1; PRKCNH1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 80-120 of Human Hint1.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42940140945587,"sku":"BS3011-50","price":254.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42940140978355,"sku":"BS3011-100","price":442.75,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_ce89602e-0cf6-4f17-89cb-7f59f9bf132e.jpg?v=1704631422","url":"https:\/\/afsbio.com\/products\/hint1-n99-polyclonal-antibody-bs3011","provider":"AFSBio Inc.","version":"1.0","type":"link"}