{"product_id":"histamine-h2-receptor-polyclonal-antibody-bt-ap03980","title":"Histamine H2 Receptor Polyclonal Antibody - BT-AP03980","description":"\u003cp\u003eHistamine H2 Receptor Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03980-20, BT-AP03980-50, BT-AP03980-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for HRH2.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HRH2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Histamine H2 Receptor Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 40098\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P25021; Mouse: P97292\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HRH2; Histamine H2 receptor; H2R; HH2R; Gastric receptor I\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3274\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240357486771,"sku":"BT-AP03980-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240357519539,"sku":"BT-AP03980-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240357552307,"sku":"BT-AP03980-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9cb0837c-5ae1-4711-92d8-2dfe6ecab2fe.png?v=1769407314","url":"https:\/\/afsbio.com\/products\/histamine-h2-receptor-polyclonal-antibody-bt-ap03980","provider":"AFSBio Inc.","version":"1.0","type":"link"}