{"product_id":"histone-deacetylase-1-polyclonal-antibody-bt-ap03984","title":"Histone deacetylase 1 Polyclonal Antibody - BT-AP03984","description":"\u003cp\u003eHistone deacetylase 1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03984-20, BT-AP03984-50, BT-AP03984-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. Histone deacetylase 1 encoded by HDAC1 belongs to the histone deacetylase\/acuc\/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HDAC1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Histone deacetylase 1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 55103\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q13547; Mouse: O09106; Rat: Q4QQW4\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HDAC1; RPD3L1; Histone deacetylase 1; HD1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3065; Mouse: 433759; Rat: 297893\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240357879987,"sku":"BT-AP03984-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240357912755,"sku":"BT-AP03984-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240357945523,"sku":"BT-AP03984-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d7297770-988e-40f9-bf50-d0af3b8475e8.png?v=1769407319","url":"https:\/\/afsbio.com\/products\/histone-deacetylase-1-polyclonal-antibody-bt-ap03984","provider":"AFSBio Inc.","version":"1.0","type":"link"}