{"product_id":"histone-deacetylase-6-polyclonal-antibody-bt-ap03986","title":"Histone deacetylase 6 Polyclonal Antibody - BT-AP03986","description":"\u003cp\u003eHistone deacetylase 6 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03986-20, BT-AP03986-50, BT-AP03986-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation\/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 6 encoded by HDAC6 belongs to class II of the histone deacetylase\/acuc\/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HDAC6\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Histone deacetylase 6 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 131431\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9UBN7; Mouse: Q9Z2V5\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 10013; Mouse: 15185\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240358076595,"sku":"BT-AP03986-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240358109363,"sku":"BT-AP03986-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240358142131,"sku":"BT-AP03986-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a8a2e328-6aa5-4931-acce-b35115323352.png?v=1769407322","url":"https:\/\/afsbio.com\/products\/histone-deacetylase-6-polyclonal-antibody-bt-ap03986","provider":"AFSBio Inc.","version":"1.0","type":"link"}