{"product_id":"histone-h1-tri-methyl-lys25-rabbit-polyclonal-antibody-es20561","title":"Histone H1 (Tri Methyl Lys25) Rabbit Polyclonal Antibody - ES20561","description":"\u003cp\u003eHistone H1 (Tri Methyl Lys25) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES20561-50, ES20561-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: H1K25ME3, HIST1H1A, H1F1, Histone H1.1, Histone H1a, HIST1H1C, H1F2, Histone H1.2, Histone H1c, Histone H1d, Histone H1s-1, HIST1H1D, H1F3, Histone H1.3, Histone H1c, Histone H1s-2, HIST1H1E, H1F4, Histone H1.4, Histone H1b, Histone H1s-4\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic Peptide of Histone H1 (Tri Methyl Lys25)\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: Histone H1\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: The antibody detects endogenous Histone H1 (Tri Methyl Lys25) protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1:1000-2000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormlation: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Placenta,\u003c\/p\u003e \n\n\u003cp\u003eObserved Band (KD): 17-25kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Function: Histones H1 are necessary for the condensation of nucleosome chains into higher order structures\u003cbr\u003e\nSimilarity: Belongs to the histone H1\/H5 family\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Nucleus Chromosome Mainly localizes in euchromatin\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: HIST1H1A\/HIST1H1C\/HIST1H1D\/HIST1H1E\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Histone H1.1\/Histone H1.2\/Histone H1.3\/Histone H1.4\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 80838\/50708\/14957\/50709\u003c\/p\u003e\n\n\u003cp\u003eRat Gene ID: 291145\/201097\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: D4A3K5\/P15865\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46314183033011,"sku":"ES20561-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46314183065779,"sku":"ES20561-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/histone-h1-tri-methyl-lys25-rabbit-polyclonal-antibody-es20561","provider":"AFSBio Inc.","version":"1.0","type":"link"}