{"product_id":"histone-h2a-x-phospho-ser139-polyclonal-antibody-bt-ap09929","title":"Histone H2A.X (Phospho Ser139) Polyclonal Antibody - BT-AP09929","description":"\u003cp\u003eHistone H2A.X (Phospho Ser139) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09929-20, BT-AP09929-50, BT-AP09929-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: H2AFX\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Histone H2A.x\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P16104; Mouse: P27661\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Histone H2A.x; H2AFX; H2AX; Histone H2A.x; H2a\/x\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3014; Mouse: 15270\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239167025331,"sku":"BT-AP09929-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239167058099,"sku":"BT-AP09929-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239167090867,"sku":"BT-AP09929-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_090a43d3-2b30-46f6-b9a6-3eca72533b2f.png?v=1769390044","url":"https:\/\/afsbio.com\/products\/histone-h2a-x-phospho-ser139-polyclonal-antibody-bt-ap09929","provider":"AFSBio Inc.","version":"1.0","type":"link"}