{"product_id":"histone-h2b-phospho-ser14-rabbit-polyclonal-antibody-bt-ap02991","title":"Histone H2B (Phospho-Ser14) Rabbit Polyclonal Antibody - BT-AP02991","description":"\u003cp\u003eHistone H2B (Phospho-Ser14) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP02991-20, BT-AP02991-50, BT-AP02991-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A| H2B| H3| and H4) form an octamer| around which approximately 146 bp of DNA is wrapped in repeating units| called nucleosomes. The linker histone| H1| interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HIST1H2BH\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Histone H2B\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q93079; Mouse: Q64478\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Histone H2B;Ser14; Histone H2B type 1-H; Histone H2B.j; H2B\/j\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8345; Mouse: 319182\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238998925491,"sku":"BT-AP02991-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238998958259,"sku":"BT-AP02991-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238998991027,"sku":"BT-AP02991-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3ef69419-142e-4603-acf3-932251e59882.png?v=1769387753","url":"https:\/\/afsbio.com\/products\/histone-h2b-phospho-ser14-rabbit-polyclonal-antibody-bt-ap02991","provider":"AFSBio Inc.","version":"1.0","type":"link"}