{"product_id":"histone-h2b-polyclonal-antibody-bs67568","title":"Histone H2B Polyclonal Antibody-BS67568","description":"\u003cp\u003eHistone H2B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS67568-50, BS67568-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P62807\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB (1\/500 - 1\/1000)\u003c\/p\u003e\n\n\u003cp\u003eBackground: Entirely replaces classical histone H2B prior nucleosome to protamine transition and probably acts as a nucleosome dissociating factor that creates a more dynamic chromatin, facilitating the large-scale exchange of histones ore component of nucleosome .Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability .DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling .Also found in fat cells, its function and the presence of post-translational modifications specific to such cells are still unclear.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was purified by immunogen affinity chromatography.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes endogenous levels of Histone H2B protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Histone H2B expression in HEK293T (A), HCT116 (B) whole cell lysates.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 15 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: H2BFL; H2BFH; H2BFG; H2BFA; H2BFK; Histone H2B type 1-C\/E\/F\/G\/I; Histone H2B.1 A; Histone H2B.a; H2B\/a; Histone H2B.g; H2B\/g; Histone H2B.h; H2B\/h; Histone H2B.k; H2B\/k; Histone H2B.l; H2B\/l\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Histone H2B. The exact sequence is proprietary.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42906348748979,"sku":"BS67568-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42906348781747,"sku":"BS67568-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_2a27e36e-c0bc-4b3f-86a2-9b8c7e211a82.jpg?v=1702918439","url":"https:\/\/afsbio.com\/products\/histone-h2b-polyclonal-antibody-bs67568","provider":"AFSBio Inc.","version":"1.0","type":"link"}