{"product_id":"histone-h3-tri-methyl-k5-polyclonal-antibody-bt-ap10017","title":"Histone H3 (Tri-Methyl-K5) Polyclonal Antibody - BT-AP10017","description":"\u003cp\u003eHistone H3 (Tri-Methyl-K5) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10017-20, BT-AP10017-50, BT-AP10017-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Signal transduction; Tags and cell markers\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HIST1H3A\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Histone H3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P68431\/Q71DI3\/P84243\/Q6NXT2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Histone H3; H3K5ME3; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3\/a; Histone H3\/b; Histone H3\/c; Histone H3\/d; Histone H3\/f; Histone H3\/h; Histone H3\/i; Histone H3\/j; Histone H3\/k; Histone H3\/l; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3D; Histone H3.2; Histone H3\/m; Histone H3\/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8350\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239167942835,"sku":"BT-AP10017-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239167975603,"sku":"BT-AP10017-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239168008371,"sku":"BT-AP10017-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_fe3ed612-d15e-4d48-abea-f5c271cddaf2.png?v=1769390057","url":"https:\/\/afsbio.com\/products\/histone-h3-tri-methyl-k5-polyclonal-antibody-bt-ap10017","provider":"AFSBio Inc.","version":"1.0","type":"link"}