{"product_id":"histone-h4-ack20-polyclonal-antibody-bs67130","title":"Histone H4 (AcK20) Polyclonal Antibody-BS67130","description":"\u003cp\u003eHistone H4 (AcK20) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS67130-50, BS67130-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P62805\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB (1\/500 - 1\/1000)\u003c\/p\u003e\n\n\u003cp\u003eBackground: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes endogenous levels of Histone H4 with a site at AcK20 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Histone H4 (AcK20) expression in A549 (A), U2OS (B) whole cell lysates.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight:  ~ 15 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: H4\/A; H4FA; H4\/I; H4FI; H4\/G; H4FG; H4\/B; H4FB; H4\/J; H4FJ; H4\/C; H4FC; H4\/H; H4FH; H4\/M; H4FM; H4\/E; H4FE; H4\/D; H4FD; H4\/K; H4FK; H4\/N; H4F2; H4FN; HIST2H4; H4\/O; H4FO; Histone H4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Histone H4 with a site at AcK20. The exact sequence is proprietary.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42908717646003,"sku":"BS67130-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42908717678771,"sku":"BS67130-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_d91a0fc3-a3f4-4273-8eb6-aa26f9f6a10f.jpg?v=1703006185","url":"https:\/\/afsbio.com\/products\/histone-h4-ack20-polyclonal-antibody-bs67130","provider":"AFSBio Inc.","version":"1.0","type":"link"}